GeneCare Research Institute Co.,Ltd.



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Research & Development

Publication List [Only Key Articles]

Takemoto M, Yamaga M, Furuichi Y, Yokote K.

Astaxanthin Improves Nonalcoholic Fatty Liver Disease in Werner Syndrome with Diabetes Mellitus. J Am Geriatr Soc. 63, 1271-3. 2015.

Sanada S, Futami K, Terada A, Yonemoto K, Ogasawara S, Akiba J, Yasumoto M, Sumi A, Ushijima K, Kamura T, Furuichi Y, Yano H.

RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer. PLoS One. 8, e72820. 2013.

De S, Kumari J, Mudgal R, Modi P, Gupta S, Futami K, Goto H, Lindor NM, Furuichi Y, Mohanty D, Sengupta S.
RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress. J Cell Sci. 125, 2509-2522. 2012.

Arai A, Chano T, Futami K, Furuichi Y, Ikebuchi K, Inui T, Tameno H, Ochi Y, Shimada T, Hisa Y, Okabe H.

RECQL1 and WRN Proteins Are Potential Therapeutic Targets in Head and Neck Squamous Cell Carcinoma. Cancer Res. 71, 4598-4607. 2011.

Kataoka K, Kono Y, Sugtimoto M, Furuichi Y, Shichiri M, Tanaka Y.

Hepatocyte-protective and anti-oxidant effects of rifampicin on human chronic hepatitis C and murine acute hepatocyte disorder. Exp Ther Med. 1, 1041. 2010.

Futami K
, Kumagai E, Makino H, Sato A, Takagi M, Shimamoto A, Furuichi Y.

Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Cancer Sci. 99, 1227-1236, 2008.

Futami K, Ishikawa Y, Goto M, Furuichi Y, Sugimoto M.

Role of WRN helicase in carcinogenesis and in resistance by cancer cells to genotoxins. Cancer Sci. 99, 843-848, 2008.

Futami K
, Kumagai E, Makino H, Goto H, Takagi M, Shimamoto A, Furuichi Y.

Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase. Cancer Sci. 99, 71-80, 2008.

Futami K, Takagi M, Shimamoto A, Sugimoto M, Furuichi Y.

Increased chemotherapeutic activity of camptothecin in cancer cells by siRNA-induced silencing of WRN helicase. Biol Pharm Bull. 30, 1958-1961, 2007.


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